One of the main aims is to provide a searchable database with quantitative information on drug targets and the prescription medicines and experimental drugs that act on them. The information in the database is presented at two levels: the initial view or landing pages for each target family provide expert-curated overviews of the key properties and selective ligands and tool compounds available. For selected targets more detailed introductory chapters for each family are available along with curated information on the pharmacological, physiological, structural, genetic and pathophysiogical properties of each target. The database is enhanced with hyperlinks to additional information in other databases including Ensembl, UniProt, PubChem, ChEMBL and DrugBank, as well as curated chemical information and literature citations in PubMed.

Harding SD, Sharman JL, Faccenda E, Southan C, Pawson AJ, Ireland S, Gray AJG, Bruce L, Alexander SPH, Anderton S, Bryant C, Davenport AP, Doerig C, Fabbro D, Levi-Schaffer F, Spedding M, Davies JA; NC-IUPHAR. (2018) The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY. Nucl. Acids Res. 46 (Issue D1): D1091-D1106. doi: 10.1093/nar/gkx1121.

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tutorial: http://www.guidetopharmacology.org/GuidetoPHARMACOLOGY_Tutorial.pdf

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Researchers should cite this work as follows:

• (2024), "PHARMACOLOGY," https://sciencegateways.org/resources/pharmacology.

  BibTex | EndNote

1. database
2. ligands
3. PHARMACOLOGY
4. Software